Gene therapy for Hemophilia B
For the millionth time– Viruses are not just pathogens that make us sick. In the modern world, viruses have been domesticated, and are now used to treat/cure diseases. Example #gazillion: Hemophilia B:...
View ArticleGene therapy might actually work for HIV-1 infection
If you had asked me 6 years ago about using gene therapy to fight HIV/AIDS, I would have given you a nice rant about how expensive it is, how non-viable it is in the places that need anti-HIV...
View ArticleGMO Virus for Nicotine Addiction
I used to think gene therapy was an absurd ‘solution’ for HIV/AIDS. Well, ‘absurd’ is putting it lightly. I thought gene therapy was a perverted solution– Even if it ‘worked’, it would only be...
View ArticleFirst viral gene therapy vector approved– Out of the trials, into the patients
Domesticating wild organisms– Whether its domesticating teosinte or aurochs, bending wild organisms to our will is always a game-changing event in human history. The domestication of viruses is no...
View ArticleGMO Herpes vs severe cancer pain
What happens when the pain gets to be too much? What happens when the drugs stop working? The physicians are giving you as much as you can take without dying, and youre still living with 7, 8, 9...
View ArticleGene therapy for Hemophilia A
So what do you do after you use a genetically modified virus to treat–>functionally cure Hemophilia B? Why, use a genetically modified virus to treat–>hopefully functionally cure Hemophilia A, of...
View ArticleLets just cure/prevent deafness while we are at it.
Lets play a game. Think of a human disease. Any disease. Viral, bacterial, genetic, acquired, anything. Im pretty sure that no matter what disease you just thought of, there is a scientist,...
View ArticleGMO virus cures kid of cancer, mainstream media finally interested
A lot of folks have been forwarding me this story from the New York Times– In Girl’s Last Hope, Altered Immune Cells Beat Leukemia It is a FANTASTIC story about a little girl who had been sick from...
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BWAHAHAHAHA GMO virus to replace pacemakers
Im seriously, you guys. ANY MEDICAL CONDITION YOU CAN THINK OF: There is a scientist, somewhere, trying to use viruses to treat/cure that condition. The latest: Direct conversion of quiescent...
View ArticleBuilding a better GMO virus for Hemophilia B
When youre trying to cure a genetic disease with a genetically modified virus, you dont have to get a perfect score. You dont have to cure everyone in the trial. You dont even really have to cure them–...
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GMO viruses for coronary artery disease
Whoda thought that injecting viruses into peoples hearts would be not only fun, but good for their health! I just wrote about this little guy that can turn regular heart muscle cells into pacemaker...
View ArticleHold off on the chemo! Herpes doesnt like it!
Hey remember how I told you all scientists are using herpes, the regular-ol much hated cold-sore virus, to treat/cure cancers? The approach has left us with miraculous effects… or no effects at all. I...
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1800 gene therapy trials
I wish I wish I wish this article was open access! ARG!! Gene therapy clinical trials worldwide to 2012 – an update This article is a great review of gene therapy as a therapy, and how it has evolved...
View ArticleNew weapon in the pipeline: GMO herpes vs Ovarian and Breast Cancer (+...
This is one of the cool ideas not included in the 1800 human gene therapy trials because its still in animal models, not humans: Preclinical Therapy of Disseminated HER-2+ Ovarian and Breast Carcinomas...
View Article‘Dismal prognosis’ with leukemia? Nothing a GMO virus cant fix.
Using a genetically modified HIV-1 to genetically modify leukemia patients T-cells to teach them how to kill the cancer? YAWN! Thats childs play, at this point. Lets give those GMO viruses a real...
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More gene therapy for more kinds of blindness!
This therapy isnt perfect, but its a cool start! Retinal gene therapy in patients with choroideremia: initial findings from a phase 1/2 clinical trial ‘Choroideremia‘ is a kind of blindness caused by...
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GMO retroviruses vs Parkinsons
Long-term safety and tolerability of ProSavin, a lentiviral vector-based gene therapy for Parkinson’s disease: a dose escalation, open-label, phase 1/2 trial 1. Start with HIV-1s ‘country cousin‘,...
View ArticleGMO virus vs B-Cell Acute Lymphoblastic Leukemia: Why is this not a standard...
WHY IS THIS NOT STANDARD THERAPY YET? Efficacy and Toxicity Management of 19-28z CAR T Cell Therapy in B Cell Acute Lymphoblastic Leukemia I wrote about this last year: ‘Dismal prognosis’ with...
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GMO in GMOs used to make GMO cells to treat HIV
You all might have heard about ‘delta32′ or ‘delta-CCR5′ people in association with HIV infection. People who naturally, by chance, have deletions and mutations in the CCR5 gene of their DNA dont make...
View ArticleGMO Virus: Long-term success treating Hemophilia B
One of my favorite stories is the tale of a GMO virus deployed to treat Hemophilia B: Gene therapy for Hemophilia B … Hemophilia B is a disease in males caused by point mutations/deletions/etc in the...
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